ESPE Yearbook of Paediatric Endocrinology

To read the full abstract: J Clin Endocrinol Metab. 2019; 104(12): 6148–6154. PMID: 31393570.Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency has an incidence of 1 in 10 000 to 20 000 in most populations. It is one of the most common monogenic autosomal recessive disorders (1). It has been suggested that the condition is common because it may confe...

To read the full abstract: JAMA 2019; 32:484–492Type 1 diabetes (T1DM) is clearly associated with higher risks for cardiovascular disease and late complications, such as retinopathy and nephropathy. A putative impact of T1DM on neurocognitive development is less clear. For example, it is unclear whether T1DM is associated with school performance in children.This study compared standardized reading and mathematics test...

To read the full abstract: Diabetologia. 2018;61:831-838T1DM in childhood and adolescence is a high burden for patients and family members. This is reflected by research that shows an increased incidence of psychiatric disorders in this patient group. Especially depression, eating disorders and anxiety disorders seem to be more prevalent. However data are mainly from small cohorts or regional...

To read the full abstract: Pediatr Diabetes. 2020 Feb;21(1):106–111. doi: 10.1111/pedi.12936. PMID: 31618523Children with type 1 diabetes (T1DM) should be screened regularly for signs of retinopathy by fundus photography in order to prevent visual impairment. According to Danish national guidelines, screening should take place at ages 12, 15, and 18 years after a minimum of 3 years of diab...

Brief summary: This international multicentre study collected data from 104 290 children and adolescents (6 months-18 years-old), to compare prevalence of diabetic ketoacidosis (DKA) at diagnosis of type 1 diabetes (T1D) before and during the COVID-19 pandemic. Prevalence of DKA at T1D diagnosis increased from 27.3% pre-pandemic to 39.4% during the pandemic, and the increased trends were associated with the pandemic containment measures.DKA is a life-thr...